Due Date: 12/15/20
Funder: Foundation for a Smoke-free World
About Foundation for a Smoke-free World
The Foundation for a Smoke-Free World, Inc. (FSFW or the Foundation) is an independent, nonprofit, tax-exempt, private foundation committed to reducing deaths and diseases caused by smoking. Their mission is to end smoking in this generation. To achieve this goal on a truly global scale, they strive to identify and address the unique needs of the developing world as they relate to tobacco cessation and harm reduction.
About the Opportunity
The Foundation for a Smoke-free World is seeking to conduct research at the nexus of COVID-19, smoking, and nicotine that will require significant collaboration and research efforts with outside experts and organizations. The Foundation seeks to advance knowledge of value to science and policy in these areas. The selected organization(s) will implement a range of projects relevant to the global pandemic, including well-designed and comprehensive pre-clinical, clinical, and epidemiological studies, to better understand the associations between smoking and/or nicotine use, and COVID-19 infection and outcomes.
Scope of Work
The Foundation plans to commission epidemiological, pre-clinical, and clinical research at the intersection of smoking and COVID-19 which may encompass some of the questions and research topics below. These questions are designed to be a guide only to this request for proposals. The Foundation will also consider proposals that answer research and innovation priorities, related to the impact of COVID-19, outside of this list.
- What is the relationship between smoking status and COVID-19 infection and/or outcomes?
- The association between smoking and COVID 19 in relation to the likelihood of infection, hospitalization, and severity of disease
- Testing of a representative population of smokers for COVID-19 development and severity
- Identification of other aspects of nicotine product use that may confer protection or harm and how these effects are asserted
- What is the relationship between nicotine and COVID-19 infection and/or outcomes?
- In vivo and in vitro models addressing specific receptors and pathways by which the virus gains access to cells and/or leads to progressive disease
- Studies that would demonstrate mechanisms of action established with pre-clinical and population-based evidence
- What innovative interventions are required to ensure populations are able to adopt healthier lifestyle behaviors in the wake of COVID-19?
- Interventions that use behavioral economic principles and interactive technologies to enhance physical activity and reduce smoking
- Final report detailing study findings
- Public dissemination of findings, including publication in academic journals, where relevant
- For scoping grants, it is expected that a full research proposal would be submitted to the Foundation upon project completion
- The Foundation encourages participation by groups whose work aligns with the Foundation’s mission to eliminate smoking within a generation. These groups may include institutions of higher education, nonprofits, commercial enterprises, governmental agencies, or other research-based organizations.
- Applicants should have a proven track record suitable for the area of research proposed. Previous research of tobacco and/or nicotine is appreciated but is not a requirement for funding.
- Successful applicants will likely have an interdisciplinary group of key personnel who can approach this project from their individual fields of expertise (e.g. epidemiologists, clinicians, behavioral economists, basic scientists, and public health specialists).
- The Foundation expects successful applicants to conduct research and publish findings according to Open Science principles, including: declaring hypotheses and proposed analyses up front; making raw data available for analysis; publishing all results, whether positive or negative; and publishing in journals that offer open access.
- Applicants should be aware that the Foundation’s Initial funding came from Phillip Morris International (PMI). The Foundation has a nonprofit status as a US 501(c)(3) organization, and by law and policy must operate completely independently from PMI, and cannot engage in activities designed to support PMI’s interests. Further, PMI can have no involvement or say in the Foundation’s work.
Proposals are due December 15, 2020, by 9:00 am EST.